SERCA2 ATPase Rabbit pAb - diagbio | 戴格生物

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SERCA2 ATPase Rabbit pAb

db21191

年底大促

Datasheet

Product Name : SERCA2 ATPase Rabbit pAb

Cat.No.: db21191

Synonyms : DD; DAR; ATP2B; SERCA2

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated

Background This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of the skeletal muscle. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Other types of mutations in this gene have been associated with various forms of muscular dystrophies. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2019]
Immunogen A synthetic peptide of human SERCA2 ATPase
Gene ID 488
Swiss Prot P16615
Synonyms DD; DAR; ATP2B; SERCA2
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC/IF, FC
Recommended dilution WB: 1:1000
IHC: 1:50
ICC/IF: 1:50
FC: 1:20
Calculated MW 115 kDa
Observed MW 115 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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