GTPBP4 Rabbit pAb - diagbio | 戴格生物

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GTPBP4 Rabbit pAb

db21246

年底大促

Datasheet

Product Name : GTPBP4 Rabbit pAb

Cat.No.: db21246

Synonyms : NGB; CRFG; NOG1

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated

Background GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human GTPBP4/NOG1
Gene ID 23560
Swiss Prot Q9BZE4
Synonyms NGB; CRFG; NOG1
Reactivity Human
Application WB, IHC, FC, IP
Recommended dilution WB: 1:1000
IHC: 1:50
FC: 1:20
IP: 1:20
Calculated MW 74 kDa
Observed MW 80 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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