FE65 Rabbit pAb - diagbio | 戴格生物

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FE65 Rabbit pAb

db21248

年底大促

Datasheet

Product Name : FE65 Rabbit pAb

Cat.No.: db21248

Synonyms : RIR; FE65; MGC:9072

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated

Background The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2012]
Immunogen A synthetic peptide of human FE65
Gene ID 322
Swiss Prot O00213
Synonyms RIR; FE65; MGC:9072
Reactivity Human
Application WB, IHC, ICC/IF
Recommended dilution WB: 1:1000
IHC: 1:201:20
Calculated MW 77 kDa
Observed MW 100 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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