C2 Rabbit pAb - diagbio | 戴格生物

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C2 Rabbit pAb

db21303

年底大促

Datasheet

Product Name : C2 Rabbit pAb

Cat.No.: db21303

Synonyms : CO2; ARMD14

Application：

Reactivity : Human, Mouse

Host species : Rabbit

Un-conjugated

Background Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.[provided by RefSeq, Mar 2009]
Immunogen A synthetic peptide of human C2
Gene ID 717
Swiss Prot P06681
Synonyms CO2; ARMD14
Reactivity Human, Mouse
Application WB
Recommended dilution WB: 1:1000
Calculated MW 83 kDa
Observed MW 100 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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