Phospho-HDAC5 (Ser498) Rabbit pAb - diagbio | 戴格生物

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Phospho-HDAC5 (Ser498) Rabbit pAb

db21377

年底大促

Datasheet

Product Name : Phospho-HDAC5 (Ser498) Rabbit pAb

Cat.No.: db21377

Synonyms : HD5; NY-CO-9

Application：

Reactivity : Human, Mouse

Host species : Rabbit

Un-conjugated

Background Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser498 of human HDAC5
Gene ID 10014
Swiss Prot Q9UQL6
Synonyms HD5; NY-CO-9
Reactivity Human, Mouse
Application WB
Recommended dilution WB: 1:1000
Calculated MW 122 kDa
Observed MW 140 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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