Cathepsin S Rabbit pAb - diagbio | 戴格生物

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Cathepsin S Rabbit pAb

db21511

年底大促

Datasheet

Product Name : Cathepsin S Rabbit pAb

Cat.No.: db21511

Synonyms : CTSS

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated

Background The preproprotein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that participates in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. The mature protein cleaves the invariant chain of MHC class II molecules in endolysosomal compartments and enables the formation of antigen-MHC class II complexes and the proper display of extracellular antigenic peptides by MHC-II. The mature protein also functions as an elastase over a broad pH range. When secreted from cells, this protein can remodel components of the extracellular matrix such as elastin, collagen, and fibronectin. This gene is implicated in the pathology of many inflammatory and autoimmune diseases and, given its elastase activity, plays a significant role in some pulmonary diseases. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2020]
Immunogen A synthetic peptide of human Cathepsin S
Gene ID 1520
Swiss Prot P25774
Synonyms CTSS
Reactivity Human
Application WB, IHC, ICC/IF
Recommended dilution WB: 1:1000
IHC: 1:20
ICC/IF: 1:20
Calculated MW 38 kDa
Observed MW 38 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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