HSD11B1 Rabbit pAb - diagbio | 戴格生物

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HSD11B1 Rabbit pAb

db21532

年底大促

Datasheet

Product Name : HSD11B1 Rabbit pAb

Cat.No.: db21532

Synonyms : HDL; 11-DH; HSD11; HSD11B; HSD11L; CORTRD2; SDR26C1; 11-beta-HSD1

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated

Background The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, May 2011]
Immunogen A synthetic peptide of human HSD11B1
Gene ID 3290
Swiss Prot P28845
Synonyms HDL; 11-DH; HSD11; HSD11B; HSD11L; CORTRD2; SDR26C1; 11-beta-HSD1
Reactivity Human
Application WB, IHC, ICC/IF
Recommended dilution WB: 1:2000-1:10000
IHC: 1:20
ICC/IF: 1:20
Calculated MW 32 kDa
Observed MW 32 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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