Product Name :
Ku80 Rabbit pAb
Cat.No.:
db21544
Synonyms :
KU80; KUB2; Ku86; NFIV; KARP1; KARP-1
Reactivity :
Human
Host species :
Rabbit
Conjugation/Formulation:Un-conjugated
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Background
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]
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Immunogen
A synthetic peptide of human Ku80
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Gene ID
7520
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Swiss Prot
P13010
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Synonyms
KU80; KUB2; Ku86; NFIV; KARP1; KARP-1
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Reactivity
Human
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Application
WB, IHC, ICC/IF, FC
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Recommended dilution
WB: 1:1000
IHC: 1:50
ICC/IF: 1:50
FC: 1:20
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Calculated MW
83 kDa
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Observed MW
83 kDa
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Host species
Rabbit
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Clonality
Polyclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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20μL
598
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50μL
998
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100μL
1798
- 货期:现货
For research use only. Not intended for diagnostic.