Product Name :
PLCG1 Rabbit pAb
Cat.No.:
db21711
Synonyms :
PLC1; NCKAP3; PLC-II; PLC148; PLCgamma1
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
Conjugation/Formulation:Un-conjugated
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Background
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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Immunogen
A synthetic peptide of human Phospholipase C gamma 1/PLC-gamma-1
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Gene ID
5335
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Swiss Prot
P19174
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Synonyms
PLC1; NCKAP3; PLC-II; PLC148; PLCgamma1
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Reactivity
Human, Mouse, Rat
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Application
WB, ICC/IF, FC, IP
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Recommended dilution
WB: 1:2000
ICC/IF: 1:50
FC: 1:20
IP: 1:20
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Calculated MW
149 kDa
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Observed MW
149 kDa
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Host species
Rabbit
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Clonality
Polyclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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订购信息
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Package
Price (RMB)
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20μL
598
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50μL
998
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100μL
1798
- 货期:现货
For research use only. Not intended for diagnostic.