CD38 (DGR32870) Mouse mAb - diagbio | 戴格生物

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CD38 (DGR32870) Mouse mAb

db21759

Datasheet

Product Name : CD38 (DGR32870) Mouse mAb

Cat.No.: db21759

Synonyms : ADPRC1; cADPR1; ADPRC 1

Application：

Reactivity : Human

Host species : Mouse

Un-conjugated

Background The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Immunogen Recombinant protein of human CD38
Gene ID 952
Swiss Prot P28907
Synonyms ADPRC1; cADPR1; ADPRC 1
Reactivity Human
Application ICC/IF, FC
Recommended dilution ICC/IF: 1:100-1:200
FC: 1:500-1:1000
Calculated MW 34 kDa
Host species Mouse
Clonality Monoclonal
Clonality No. DGR32870
Isotype IgG1
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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