CNGA1 (DGR32873) Mouse mAb
Product Name :
CNGA1 (DGR32873) Mouse mAb
Cat.No.:
db21762
Synonyms :
CNG; CNCG1
Reactivity :
Mouse, Rat
Host species :
Mouse
Conjugation/Formulation：Un-conjugated
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Background
Pore-forming subunit of the rod cyclic nucleotide-gated channel. Mediates rod photoresponses at dim light converting transient changes in intracellular cGMP levels into electrical signals. In the dark, cGMP levels are high and keep the channel open enabling a steady inward current carried by Na+ and Ca2+ ions that leads to membrane depolarization and neurotransmitter release from synaptic terminals. Upon photon absorption cGMP levels decline leading to channel closure and membrane hyperpolarization that ultimately slows neurotransmitter release and signals the presence of light, the end point of the phototransduction cascade.
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Immunogen
Recombinant protein of mouse CNGA1
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Gene ID
281700
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Swiss Prot
Q00194
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Synonyms
CNG; CNCG1
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Reactivity
Mouse, Rat
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Application
IHC-P
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Recommended dilution
IHC-P: 1:100
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Calculated MW
80 kDa
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Host species
Mouse
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Clonality
Monoclonal
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Clonality No.
DGR32873
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Isotype
IgG1
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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10μL
398
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20μL
698
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50μL
1398
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100μL
2398
For research use only. Not intended for diagnostic.
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