HLA-DR (DGR32914) Mouse mAb - diagbio | 戴格生物

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HLA-DR (DGR32914) Mouse mAb

db21803

年底大促

Datasheet

Product Name : HLA-DR (DGR32914) Mouse mAb

Cat.No.: db21803

Synonyms : HLA-DRA1

Application：

Reactivity : Human

Host species : Mouse

Un-conjugated

Background HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. This molecule is expressed on the surface of various antigen presenting cells such as B lymphocytes, dendritic cells, and monocytes/macrophages, and plays a central role in the immune system and response by presenting peptides derived from extracellular proteins, in particular, pathogen-derived peptides to T cells. The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. [provided by RefSeq, Aug 2020]
Immunogen Recombinant protein of human HLA-DR
Gene ID 3122
Swiss Prot P01903
Synonyms HLA-DRA1
Reactivity Human
Application WB, IHC-P, ICC/IF, FC
Recommended dilution WB: 1:1000
IHC-P: 1:100-1:200
ICC/IF: 1:200-1:1000
FC: 1:5000-1:50000
Calculated MW 29 kDa
Observed MW 30-40 kDa
Host species Mouse
Clonality Monoclonal
Clonality No. DGR32914
Isotype IgG1
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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