PAR4 Rabbit pAb - diagbio | 戴格生物

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PAR4 Rabbit pAb

db21852

Datasheet

Product Name : PAR4 Rabbit pAb

Cat.No.: db21852

Synonyms : PAR4; Par-4

Application : WB, IP

Reactivity : Human, Mouse

Host species : Rabbit

Background This gene encodes a tumor suppressor protein that selectively induces apoptosis in cancer cells through intracellular and extracellular mechanisms. The intracellular mechanism involves the inhibition of pro-survival pathways and the activation of Fas-mediated apoptosis, while the extracellular mechanism involves the binding of a secreted form of this protein to glucose regulated protein 78 (GRP78) on the cell surface, which leads to activation of the extrinsic apoptotic pathway. This gene is located on the unstable human chromosomal 12q21 region and is often deleted or mutated different tumors. The encoded protein also plays an important role in the progression of age-related diseases. [provided by RefSeq, Aug 2017]
Immunogen A synthetic peptide of human PAR4
Gene ID 5074
Swiss Prot Q96IZ0
Synonyms PAR4; Par-4
Reactivity Human, Mouse
Application WB, IP
Recommended dilution WB: 1:2000-1:10000
IP: 1:20
Calculated MW 37 kDa
Observed MW 41 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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