Product Name :
MBNL1 Rabbit pAb
Cat.No.:
db21898
Synonyms :
EXP; MBNL
Reactivity :
Human, Mouse
Host species :
Rabbit
Conjugation/Formulation:Un-conjugated
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Background
This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities. [provided by RefSeq, Sep 2015]
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Immunogen
A synthetic peptide of human MBNL1
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Gene ID
4154
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Swiss Prot
Q9NR56
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Synonyms
EXP; MBNL
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Reactivity
Human, Mouse
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Application
WB
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Recommended dilution
WB: 1:1000
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Calculated MW
42 kDa
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Observed MW
42 kDa
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Host species
Rabbit
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Clonality
Polyclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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20μL
598
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50μL
998
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100μL
1798
- 货期:现货
For research use only. Not intended for diagnostic.