MMP17 Rabbit pAb - diagbio | 戴格生物

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MMP17 Rabbit pAb

db21980

年底大促

Datasheet

Product Name : MMP17 Rabbit pAb

Cat.No.: db21980

Synonyms : MMP-17; MT4MMP; MTMMP4; MT4-MMP

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated

Background This gene encodes a member of the peptidase M10 family and membrane-type subfamily of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Members of this subfamily contain a transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. The encoded preproprotein is proteolytically processed to generate the mature protease. This protein is unique among the membrane-type matrix metalloproteinases in that it is anchored to the cell membrane via a glycosylphosphatidylinositol (GPI) anchor. Elevated expression of the encoded protein has been observed in osteoarthritis and multiple human cancers. [provided by RefSeq, Jan 2016]
Immunogen A synthetic peptide of human MT4-MMP
Gene ID 4326
Swiss Prot Q9ULZ9
Synonyms MMP-17; MT4MMP; MTMMP4; MT4-MMP
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC/IF
Recommended dilution WB: 1:1000
IHC: 1:20
ICC/IF: 1:20
Calculated MW 67 kDa
Observed MW 63 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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