PDGFB (DGR33127) Rat mAb - diagbio | 戴格生物

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PDGFB (DGR33127) Rat mAb

db22016

年底大促

Datasheet

Product Name : PDGFB (DGR33127) Rat mAb

Cat.No.: db22016

Synonyms : SIS; SSV; IBGC5; PDGF2; c-sis; PDGF-2

Application：

Reactivity : Human

Host species : Rat

Un-conjugated

Background This gene encodes a member of the protein family comprised of both platelet-derived growth factors (PDGF) and vascular endothelial growth factors (VEGF). The encoded preproprotein is proteolytically processed to generate platelet-derived growth factor subunit B, which can homodimerize, or alternatively, heterodimerize with the related platelet-derived growth factor subunit A. These proteins bind and activate PDGF receptor tyrosine kinases, which play a role in a wide range of developmental processes. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 17, at sites where this gene and that for collagen type 1, alpha 1 are located, are associated with dermatofibrosarcoma protuberans, a rare skin tumor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]
Immunogen Recombinant protein of human PDGFB
Gene ID 5155
Swiss Prot P01127
Synonyms SIS; SSV; IBGC5; PDGF2; c-sis; PDGF-2
Reactivity Human
Application IHC-P
Recommended dilution IHC-P: 1:200-1:500
Calculated MW 27 kDa
Host species Rat
Clonality Monoclonal
Clonality No. DGR33127
Isotype IgG2b
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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