CD45RA (DGR33186) Mouse mAb
Product Name :
CD45RA (DGR33186) Mouse mAb
Cat.No.:
db22075
Synonyms :
LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180; IMD105
Reactivity :
Human
Host species :
Mouse
Conjugation/Formulation：Un-conjugated
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Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]
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Immunogen
Recombinant protein of human CD45RA
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Gene ID
5788
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Swiss Prot
P08575-8
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Synonyms
LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180; IMD105
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Reactivity
Human
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Application
IHC-P, FC
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Recommended dilution
IHC-P: 1:1000-1:5000
FC: 1:200-1:1000
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Calculated MW
138 kDa
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Host species
Mouse
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Clonality
Monoclonal
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Clonality No.
DGR33186
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Isotype
IgG1
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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10μL
398
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20μL
698
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50μL
1398
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100μL
2398
- 货期：现货
For research use only. Not intended for diagnostic.
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