E2F2 Rabbit pAb - diagbio | 戴格生物

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E2F2 Rabbit pAb

db2210

年底大促

Datasheet

Product Name : E2F2 Rabbit pAb

Cat.No.: db2210

Synonyms : E2F-2

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated

Background The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F3, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner, and it exhibits overall 46% amino acid identity to E2F1. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human E2F2
Gene ID 1870
Swiss Prot Q14209
Synonyms E2F-2
Reactivity Human, Mouse, Rat
Application WB, FC
Recommended dilution WB: 1:1000-1:5000
FC: 1:20-1:100
Calculated MW 48 kDa
Observed MW 48 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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