Product Name :
TAB3 Rabbit pAb
Cat.No.:
db22124
Synonyms :
NAP1; MAP3K7IP3
Reactivity :
Human, Mouse
Host species :
Rabbit
Conjugation/Formulation：Un-conjugated
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Background
The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
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Immunogen
A synthetic peptide of human TAB3
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Gene ID
257397
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Swiss Prot
Q8N5C8
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Synonyms
NAP1; MAP3K7IP3
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Reactivity
Human, Mouse
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Application
WB, ICC/IF
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Recommended dilution
WB: 1:1000
ICC/IF: 1:20
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Calculated MW
79 kDa
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Observed MW
82 kDa
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Host species
Rabbit
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Clonality
Polyclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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20μL
598
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50μL
998
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100μL
1798
- 货期：现货
For research use only. Not intended for diagnostic.
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