TPA Tissue Plasminogen Activator Rabbit pAb - diagbio | 戴格生物

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TPA Tissue Plasminogen Activator Rabbit pAb

db2219

年底大促

Datasheet

Product Name : TPA Tissue Plasminogen Activator Rabbit pAb

Cat.No.: db2219

Synonyms : TPA; T-PA

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated

Background This gene encodes tissue-type plasminogen activator, a secreted serine protease that converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. The encoded preproprotein is proteolytically processed by plasmin or trypsin to generate heavy and light chains. These chains associate via disulfide linkages to form the heterodimeric enzyme. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, while decreased activity leads to hypofibrinolysis, which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
Immunogen A synthetic peptide of human TPA Tissue Plasminogen Activator
Gene ID 5327
Swiss Prot P00750
Synonyms TPA; T-PA
Reactivity Human, Mouse, Rat
Application WB, IHC
Recommended dilution WB: 1:1000-1:2000
IHC: 1:20-1:100
Calculated MW 63 kDa
Observed MW 63 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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