Product Name :
DAB2 Rabbit pAb
Cat.No.:
db22372
Synonyms :
DOC2; DOC-2
Reactivity :
Human
Host species :
Rabbit
Conjugation/Formulation：Un-conjugated
-
Background
This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
-
Immunogen
A synthetic peptide of human DAB2
-
Gene ID
1601
-
Swiss Prot
P98082
-
Synonyms
DOC2; DOC-2
-
Reactivity
Human
-
Application
WB, ICC/IF, FC, IP
-
Recommended dilution
WB: 1:2000
ICC/IF: 1:50
FC: 1:20
IP: 1:20
-
Calculated MW
83 kDa
-
Observed MW
96 kDa
-
Host species
Rabbit
-
Clonality
Polyclonal
-
Isotype
IgG
-
Purity
Affinity Purification
-
Conjugation
Un-conjugated
-
Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
-
Package
Price (RMB)
-
20μL
598
-
50μL
998
-
100μL
1798
- 货期：现货
For research use only. Not intended for diagnostic.
浙公网安备 33010602008812号