mGluR1a Rabbit pAb - diagbio | 戴格生物

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mGluR1a Rabbit pAb

db22382

年底大促

Datasheet

Product Name : mGluR1a Rabbit pAb

Cat.No.: db22382

Synonyms : MGLU1; SCA44; GPRC1A; MGLUR1; SCAR13; PPP1R85

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated

Background This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
Immunogen A synthetic peptide of human mGluR1a
Gene ID 2911
Swiss Prot Q13255
Synonyms MGLU1; SCA44; GPRC1A; MGLUR1; SCAR13; PPP1R85
Reactivity Human, Mouse, Rat
Application WB
Recommended dilution WB: 1:1000
Calculated MW 132 kDa
Observed MW 125,250 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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