Phospho-PDGF Receptor beta (Tyr771) Rabbit pAb - diagbio | 戴格生物

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Phospho-PDGF Receptor beta (Tyr771) Rabbit pAb

db2252

年底大促

Datasheet

Product Name : Phospho-PDGF Receptor beta (Tyr771) Rabbit pAb

Cat.No.: db2252

Synonyms : Pdgfr; CD140b; PDGFR-1; AI528809

Application：

Reactivity : Human, Mouse

Host species : Rabbit

Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated Un-conjugated

Background This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. [provided by RefSeq, Jun 2013]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Tyr771 of human PDGF Receptor beta
Gene ID 18596
Swiss Prot P05622
Synonyms Pdgfr; CD140b; PDGFR-1; AI528809
Reactivity Human, Mouse
Application WB, IP
Recommended dilution WB: 1:1000
IP: 1:20
Calculated MW 123 kDa
Observed MW 190 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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