NEDD8 Activating Enzyme E1C Rabbit pAb - diagbio | 戴格生物

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NEDD8 Activating Enzyme E1C Rabbit pAb

db22541

年底大促

Datasheet

Product Name : NEDD8 Activating Enzyme E1C Rabbit pAb

Cat.No.: db22541

Synonyms : NAE2; UBE1C; hUBA3

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated

Background The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human UBA3
Gene ID 9039
Swiss Prot Q8TBC4
Synonyms NAE2; UBE1C; hUBA3
Reactivity Human, Mouse, Rat
Application WB
Recommended dilution WB: 1:2000-1:10000
Calculated MW 52 kDa
Observed MW 52 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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