RASSF1 Rabbit pAb - diagbio | 戴格生物

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RASSF1 Rabbit pAb

db22609

年底大促

Datasheet

Product Name : RASSF1 Rabbit pAb

Cat.No.: db22609

Synonyms : 123F2; RDA32; NORE2A; RASSF1A; REH3P21

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated

Background This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, May 2011]
Immunogen A synthetic peptide of human RASSF1
Gene ID 11186
Swiss Prot Q9NS23
Synonyms 123F2; RDA32; NORE2A; RASSF1A; REH3P21
Reactivity Human
Application WB, IHC
Recommended dilution WB: 1:1000
IHC: 1:20
Calculated MW 39 kDa
Observed MW 39 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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