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CDKN2A/p16INK4a (DGR33739) Rat mAb (PBS Only)
db22628-PBS
Datasheet

Product Name : CDKN2A/p16INK4a (DGR33739) Rat mAb (PBS Only)

Cat.No.: db22628-PBS

Synonyms : Arf; p16; MTS1; Pctr1; p19ARF; p16INK4a; p19; ARF-INK4a; INK4a-ARF; Ink4a/Arf; p16(INK4a)

Application:

Reactivity : Mouse

Host species : Rat

Conjugation/Formulation:PBS Only

  • Background Enables MDM2/MDM4 family protein binding activity; enzyme inhibitor activity; and protein N-terminus binding activity. Involved in several processes, including negative regulation of lymphocyte proliferation; positive regulation of apoptotic process; and regulation of transcription, DNA-templated. Acts upstream of or within several processes, including negative regulation of cellular protein metabolic process; negative regulation of mammary gland epithelial cell proliferation; and positive regulation of apoptotic process involved in mammary gland involution. Located in cytoplasm and granular component. Part of protein-containing complex. Is expressed in several structures, including bone marrow; central nervous system; dorsal root ganglion; eye; and testis. Human ortholog(s) of this gene implicated in several diseases, including breast cancer (multiple); carcinoma (multiple); hematologic cancer (multiple); melanoma (multiple); and nervous system cancer (multiple). Orthologous to human CDKN2A (cyclin dependent kinase inhibitor 2A). [provided by Alliance of Genome Resources, Apr 2022]
  • Immunogen Recombinant protein of mouse CDKN2A/p16INK4a
  • Gene ID 12578
  • Swiss Prot P51480
  • Synonyms Arf; p16; MTS1; Pctr1; p19ARF; p16INK4a; p19; ARF-INK4a; INK4a-ARF; Ink4a/Arf; p16(INK4a)
  • Reactivity Mouse
  • Application IHC-P
  • Calculated MW 18 kDa
  • Host species Rat
  • Clonality Monoclonal
  • Clonality No. DGR33739
  • Isotype IgG2a
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Concentration 1 mg/mL
  • Formulation PBS Only
  • Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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  • 货期:现货
For research use only. Not intended for diagnostic.