Product Name :
Cip4 Rabbit pAb
Cat.No.:
db2267
Synonyms :
STP; CIP4; HSTP; STOT; TRIP-10
Reactivity :
Human
Host species :
Rabbit
Conjugation/Formulation:Un-conjugated
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Background
Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.
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Immunogen
A synthetic peptide of human Cip4
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Gene ID
9322
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Swiss Prot
Q15642
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Synonyms
STP; CIP4; HSTP; STOT; TRIP-10
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Reactivity
Human
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Application
WB
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Recommended dilution
WB: 1:1000-1:5000
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Calculated MW
68 kDa
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Observed MW
80 kDa
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Host species
Rabbit
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Clonality
Polyclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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20μL
598
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50μL
998
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100μL
1798
- 货期:现货
For research use only. Not intended for diagnostic.