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CNOT7 Rabbit pAb

Product Name : CNOT7 Rabbit pAb

Cat.No.: db228

Synonyms : Caf1; Pop2; CAF-1; AU022737

Application:

Reactivity : Human, Mouse, Rat

Host species : Rabbit

  • Background Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Required for miRNA-mediated mRNA deadenylation.
  • Immunogen A synthetic peptide of mouse CNOT7
  • Gene ID 18983
  • Swiss Prot Q60809
  • Synonyms Caf1; Pop2; CAF-1; AU022737
  • Reactivity Human, Mouse, Rat
  • Application WB, IHC, FC, IP
  • Recommended dilution WB: 1:1000
    IHC: 1:200
    FC: 1:100
    IP: 1:20
  • Calculated MW 33 kDa
  • Observed MW 33 kDa
  • Host species Rabbit
  • Clonality Polyclonal
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
  • Package Price (RMB)
  • 20μL 598
  • 50μL 998
  • 100μL 1798
  • 货期:现货
For research use only. Not intended for diagnostic.