Product Name :
CNOT7 Rabbit pAb
Cat.No.:
db228
Synonyms :
Caf1; Pop2; CAF-1; AU022737
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
Conjugation/Formulation:Un-conjugated
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Background
Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT8. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Required for miRNA-mediated mRNA deadenylation.
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Immunogen
A synthetic peptide of mouse CNOT7
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Gene ID
18983
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Swiss Prot
Q60809
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Synonyms
Caf1; Pop2; CAF-1; AU022737
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Reactivity
Human, Mouse, Rat
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Application
WB, IHC, FC, IP
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Recommended dilution
WB: 1:1000
IHC: 1:200
FC: 1:100
IP: 1:20
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Calculated MW
33 kDa
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Observed MW
33 kDa
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Host species
Rabbit
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Clonality
Polyclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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20μL
598
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50μL
998
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100μL
1798
- 货期:现货
For research use only. Not intended for diagnostic.