Spry-2 Rabbit pAb - diagbio | 戴格生物

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Spry-2 Rabbit pAb

db22903

年底大促

Datasheet

Product Name : Spry-2 Rabbit pAb

Cat.No.: db22903

Synonyms : IGAN3; hSPRY2

Application：

Reactivity : Human, Rat

Host species : Rabbit

Un-conjugated

Background This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human Spry-2
Gene ID 10253
Swiss Prot O43597
Synonyms IGAN3; hSPRY2
Reactivity Human, Rat
Application WB, IHC, ICC/IF, IP
Recommended dilution WB: 1:1000
IHC: 1:20
ICC/IF: 1:20
IP: 1:20
Calculated MW 35 kDa
Observed MW 35 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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