Ubiquitin Protein Ligase E3A Rabbit pAb - diagbio | 戴格生物

产品中心 Products Center

您当前的位置：

Ubiquitin Protein Ligase E3A Rabbit pAb

db22909

年底大促

Datasheet

Product Name : Ubiquitin Protein Ligase E3A Rabbit pAb

Cat.No.: db22909

Synonyms : AS; ANCR; E6-AP; HPVE6A; EPVE6AP

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated

Background This gene encodes an E3 ubiquitin-protein ligase, part of the ubiquitin protein degradation system. This imprinted gene is maternally expressed in brain and biallelically expressed in other tissues. Maternally inherited deletion of this gene causes Angelman Syndrome, characterized by severe motor and intellectual retardation, ataxia, hypotonia, epilepsy, absence of speech, and characteristic facies. The protein also interacts with the E6 protein of human papillomavirus types 16 and 18, resulting in ubiquitination and proteolysis of tumor protein p53. Alternative splicing of this gene results in three transcript variants encoding three isoforms with different N-termini. Additional transcript variants have been described, but their full length nature has not been determined. [provided by RefSeq, Jul 2008]
Immunogen Recombinant protein of human UBE3A
Gene ID 7337
Swiss Prot Q05086
Synonyms AS; ANCR; E6-AP; HPVE6A; EPVE6AP
Reactivity Human, Mouse, Rat
Application WB, ICC/IF, FC, IP
Recommended dilution WB: 1:1000
ICC/IF: 1:20
FC: 1:20
IP: 1:20
Calculated MW 101 kDa
Observed MW 101 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

订购信息