SRF (DGR34300) Rat mAb - diagbio | 戴格生物

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SRF (DGR34300) Rat mAb

db23189

Datasheet

Product Name : SRF (DGR34300) Rat mAb

Cat.No.: db23189

Synonyms : MCM1; Serum response factor

Application：

Reactivity : Human, Mouse, Rat

Host species : Rat

Un-conjugated

Background This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]
Immunogen Recombinant protein of human SRF
Gene ID 6722
Swiss Prot P11831
Synonyms MCM1; Serum response factor
Reactivity Human, Mouse, Rat
Application WB, IHC-P, IP
Recommended dilution WB: 1:1000
IHC-P: 1:200-1:500
IP: 1:20
Calculated MW 52 kDa
Observed MW 67, 57 kDa
Host species Rat
Clonality Monoclonal
Clonality No. DGR34300
Isotype IgG2a
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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