alpha 2 Macroglobulin Rabbit pAb - diagbio | 戴格生物

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alpha 2 Macroglobulin Rabbit pAb

db23609

年底大促

Datasheet

Product Name : alpha 2 Macroglobulin Rabbit pAb

Cat.No.: db23609

Synonyms : A2MD; CPAMD5; FWP007; S863-7

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated

Background The protein encoded by this gene is a protease inhibitor and cytokine transporter. It uses a bait-and-trap mechanism to inhibit a broad spectrum of proteases, including trypsin, thrombin and collagenase. It can also inhibit inflammatory cytokines, and it thus disrupts inflammatory cascades. Mutations in this gene are a cause of alpha-2-macroglobulin deficiency. This gene is implicated in Alzheimer's disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. A related pseudogene, which is also located on the p arm of chromosome 12, has been identified. [provided by RefSeq, Nov 2016]
Immunogen A synthetic peptide of human alpha 2 Macroglobulin
Gene ID 2
Swiss Prot P01023
Synonyms A2MD; CPAMD5; FWP007; S863-7
Reactivity Human
Application WB
Recommended dilution WB: 1:1000
Calculated MW 163 kDa
Observed MW 163 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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