Neutrophil Elastase Rabbit pAb - diagbio | 戴格生物

产品中心 Products Center

您当前的位置：

Neutrophil Elastase Rabbit pAb

db2388

年底大促

Datasheet

Product Name : Neutrophil Elastase Rabbit pAb

Cat.No.: db2388

Synonyms : GE; NE; HLE; HNE; ELA2; SCN1; PMN-E

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated

Background Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode structurally similar proteins. The encoded preproprotein is proteolytically processed to generate the active protease. Following activation, this protease hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix. The enzyme may play a role in degenerative and inflammatory diseases through proteolysis of collagen-IV and elastin. This protein also degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. Mutations in this gene are associated with cyclic neutropenia and severe congenital neutropenia (SCN). This gene is present in a gene cluster on chromosome 19. [provided by RefSeq, Jan 2016]
Immunogen A synthetic peptide of human Neutrophil Elastase
Gene ID 1991
Swiss Prot P08246
Synonyms GE; NE; HLE; HNE; ELA2; SCN1; PMN-E
Reactivity Human
Application WB, IHC, ICC/IF, FC
Recommended dilution WB: 1:1000
IHC: 1:50
ICC/IF: 1:50
FC: 1:20
Calculated MW 29 kDa
Observed MW 29 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

订购信息