ATF1 Rabbit pAb - diagbio | 戴格生物

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ATF1 Rabbit pAb

db2422

年底大促

Datasheet

Product Name : ATF1 Rabbit pAb

Cat.No.: db2422

Synonyms : TREB36; EWS-ATF1; FUS/ATF-1

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated Un-conjugated Un-conjugated

Background This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6. [provided by RefSeq, Aug 2010]
Immunogen A synthetic peptide of human ATF1
Gene ID 466
Swiss Prot P18846
Synonyms TREB36; EWS-ATF1; FUS/ATF-1
Reactivity Human
Application WB, ICC/IF, IP
Recommended dilution WB: 1:2000
ICC/IF: 1:20
IP: 1:20
Calculated MW 29 kDa
Observed MW 40 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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