F8 Rabbit pAb - diagbio | 戴格生物

产品中心 Products Center

您当前的位置：

F8 Rabbit pAb

db24763

年底大促

Datasheet

Product Name : F8 Rabbit pAb

Cat.No.: db24763

Synonyms : AHF; F8B; F8C; HEMA; FVIII; THPH13; DXS1253E

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated

Background This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq, Jul 2008]
Immunogen Recombinant protein of human F8
Gene ID 2157
Swiss Prot P00451
Synonyms AHF; F8B; F8C; HEMA; FVIII; THPH13; DXS1253E
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC/IF, FC
Recommended dilution WB: 1:1000
IHC: 1:500
ICC/IF: 1:500
FC: 1:200
Calculated MW 267 kDa
Observed MW 267 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

订购信息