FDPS Rabbit pAb - diagbio | 戴格生物

产品中心 Products Center

您当前的位置：

FDPS Rabbit pAb

db2478

年底大促

Datasheet

Product Name : FDPS Rabbit pAb

Cat.No.: db2478

Synonyms : FPS; FPPS; POROK9

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated

Background This gene encodes an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2008]
Immunogen A synthetic peptide of human FDPS
Gene ID 2224
Swiss Prot P14324
Synonyms FPS; FPPS; POROK9
Reactivity Human
Application WB, IHC, FC
Recommended dilution WB: 1:1000-1:5000
IHC: 1:20-1:100
FC: 1:20
Calculated MW 48 kDa
Observed MW 48 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

订购信息