Phospho-LRP6 (Ser1490) Rabbit pAb - diagbio | 戴格生物

产品中心 Products Center

您当前的位置：

Phospho-LRP6 (Ser1490) Rabbit pAb

db2542

年底大促

Datasheet

Product Name : Phospho-LRP6 (Ser1490) Rabbit pAb

Cat.No.: db2542

Synonyms : ADCAD2; STHAG7

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated

Background This gene encodes a member of the low density lipoprotein (LDL) receptor gene family. LDL receptors are transmembrane cell surface proteins involved in receptor-mediated endocytosis of lipoprotein and protein ligands. The protein encoded by this gene functions as a receptor or, with Frizzled, a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade. Through its interaction with the Wnt/beta-catenin signaling cascade this gene plays a role in the regulation of cell differentiation, proliferation, and migration and the development of many cancer types. This protein undergoes gamma-secretase dependent RIP- (regulated intramembrane proteolysis) processing but the precise locations of the cleavage sites have not been determined.[provided by RefSeq, Dec 2009]
Immunogen A synthetic phosphopeptide corresponding to residues surrounding Ser1490 of human LRP6
Gene ID 4040
Swiss Prot O75581
Synonyms ADCAD2; STHAG7
Reactivity Human
Application WB
Recommended dilution WB: 1:1000
Calculated MW 180 kDa
Observed MW 180 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

订购信息