BLNK Rabbit pAb - diagbio | 戴格生物

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BLNK Rabbit pAb

db2548

年底大促

Datasheet

Product Name : BLNK Rabbit pAb

Cat.No.: db2548

Synonyms : bca; AGM4; BASH; LY57; SLP65; BLNK-S; SLP-65

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated

Background This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012]
Immunogen A synthetic peptide of human BLNK
Gene ID 29760
Swiss Prot Q8WV28
Synonyms bca; AGM4; BASH; LY57; SLP65; BLNK-S; SLP-65
Reactivity Human, Mouse, Rat
Application WB, IHC, IP
Recommended dilution WB: 1:1000
IHC: 1:20
IP: 1:20
Calculated MW 51 kDa
Observed MW 70 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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