Product Name :
SOCS2 Rabbit pAb
Cat.No.:
db2561
Synonyms :
CIS2; SSI2; Cish2; SSI-2; SOCS-2; STATI2
Reactivity :
Human
Host species :
Rabbit
Conjugation/Formulation：Un-conjugated
-
Background
This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor. The protein encoded by this gene interacts with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R) and is thought to be involved in the regulation of IGF1R mediated cell signaling. This gene has pseudogenes on chromosomes 20 and 22. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]
-
Immunogen
A synthetic peptide of human SOCS2
-
Gene ID
8835
-
Swiss Prot
O14508
-
Synonyms
CIS2; SSI2; Cish2; SSI-2; SOCS-2; STATI2
-
Reactivity
Human
-
Application
WB, ICC/IF, IP
-
Recommended dilution
WB: 1:1000-1:5000
ICC/IF: 1:20-1:50
IP: 1:20-1:50
-
Calculated MW
22 kDa
-
Observed MW
22 kDa
-
Host species
Rabbit
-
Clonality
Polyclonal
-
Isotype
IgG
-
Purity
Affinity Purification
-
Conjugation
Un-conjugated
-
Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
-
Package
Price (RMB)
-
20μL
598
-
50μL
998
-
100μL
1798
- 货期：现货
For research use only. Not intended for diagnostic.
浙公网安备 33010602008812号