Fbx32 Rabbit pAb - diagbio | 戴格生物

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Fbx32 Rabbit pAb

db2679

年底大促

Datasheet

Product Name : Fbx32 Rabbit pAb

Cat.No.: db2679

Synonyms : Fbx32; MAFbx

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated

Background This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]
Immunogen A synthetic peptide of human Fbx32
Gene ID 114907
Swiss Prot Q969P5
Synonyms Fbx32; MAFbx
Reactivity Human, Mouse, Rat
Application WB, ICC/IF
Recommended dilution WB: 1:1000
ICC/IF: 1:50
Calculated MW 42 kDa
Observed MW 42 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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