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DROSHA Rabbit pAb

Product Name : DROSHA Rabbit pAb

Cat.No.: db2698

Synonyms : RN3; ETOHI2; RNASEN; RANSE3L; RNASE3L; HSA242976

Application:

Reactivity : Human

Host species : Rabbit

Conjugation/Formulation:Un-conjugated

  • Background This gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein complex, which catalyzes the initial processing step of microRNA (miRNA) synthesis. The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRNA) in the nucleus, yielding the precursor miRNA (pre-miRNA), which is then exported to the cytoplasm for further processing. In a human cell line lacking a functional copy of this gene, canonical miRNA synthesis is reduced. Somatic mutations in this gene have been observed in human patients with kidney cancer. [provided by RefSeq, Sep 2016]
  • Immunogen A synthetic peptide of human Drosha
  • Gene ID 29102
  • Swiss Prot Q9NRR4
  • Synonyms RN3; ETOHI2; RNASEN; RANSE3L; RNASE3L; HSA242976
  • Reactivity Human
  • Application WB, IHC, ICC/IF, FC
  • Recommended dilution WB: 1:2000-1:10000
    IHC: 1:20-1:50
    ICC/IF: 1:50
    FC: 1:20
  • Calculated MW 159 kDa
  • Observed MW 159 kDa
  • Host species Rabbit
  • Clonality Polyclonal
  • Isotype IgG
  • Purity Affinity Purification
  • Conjugation Un-conjugated
  • Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
  • Package Price (RMB)
  • 20μL 598
  • 50μL 998
  • 100μL 1798
  • 货期:现货
For research use only. Not intended for diagnostic.