HLA B7 Rabbit pAb - diagbio | 戴格生物

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HLA B7 Rabbit pAb

db2713

年底大促

Datasheet

Product Name : HLA B7 Rabbit pAb

Cat.No.: db2713

Synonyms : AS; HLAB; B-4901

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated

Background HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human HLA B7
Gene ID 3106
Swiss Prot P01889
Synonyms AS; HLAB; B-4901
Reactivity Human
Application WB, IHC
Recommended dilution WB: 1:1000-1:5000
IHC: 1:50-1:200
Calculated MW 41 kDa
Observed MW 41 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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