STAT5 Rabbit pAb - diagbio | 戴格生物

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STAT5 Rabbit pAb

db2782

年底大促

Datasheet

Product Name : STAT5 Rabbit pAb

Cat.No.: db2782

Synonyms : MGF; STAT5

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated

Background The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013]
Immunogen Recombinant protein of human STAT5A
Gene ID 6776
Swiss Prot P42230
Synonyms MGF; STAT5
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC/IF, FC, IP
Recommended dilution WB: 1:1000
IHC: 1:200
ICC/IF: 1:50
FC: 1:20
IP: 1:50
Calculated MW 90 kDa
Observed MW 90 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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