Thyroglobulin Rabbit pAb - diagbio | 戴格生物

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Thyroglobulin Rabbit pAb

db2901

年底大促

Datasheet

Product Name : Thyroglobulin Rabbit pAb

Cat.No.: db2901

Synonyms : TGN; AITD3

Application：

Reactivity : Human, Mouse, Rat

Host species : Rabbit

Un-conjugated

Background Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq, Nov 2009]
Immunogen A synthetic peptide of human Thyroglobulin
Gene ID 7038
Swiss Prot P01266
Synonyms TGN; AITD3
Reactivity Human, Mouse, Rat
Application WB, IHC, ICC/IF, FC
Recommended dilution WB: 1:2000-1:10000
IHC: 1:50-1:200
ICC/IF: 1:20-1:50
FC: 1:20
Calculated MW 305 kDa
Observed MW 305 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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