Product Name :
PKC delta Rabbit pAb
Cat.No.:
db2975
Synonyms :
Pkcd; PKC[d]; AI385711; PKCdelta; D14Ertd420e
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
Conjugation/Formulation:Un-conjugated
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Background
Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti-apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression, is required for oxygen radical production by NADPH oxidase and acts as positive or negative regulator in platelet functional responses. Negatively regulates B cell proliferation and also has an important function in self-antigen induced B cell tolerance induction. Upon DNA damage, activates the promoter of the death-promoting transcription factor BCLAF1/Btf to trigger BCLAF1-mediated p53/TP53 gene transcription and apoptosis.
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Immunogen
Recombinant protein of human PKC delta
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Gene ID
18753
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Swiss Prot
P28867
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Synonyms
Pkcd; PKC[d]; AI385711; PKCdelta; D14Ertd420e
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Reactivity
Human, Mouse, Rat
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Application
WB, IHC, ICC/IF, FC
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Recommended dilution
WB: 1:1000
IHC: 1:20-1:500
ICC/IF: 1:100
FC: 1:50
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Calculated MW
78 kDa
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Observed MW
78 kDa
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Host species
Rabbit
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Clonality
Polyclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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订购信息
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Package
Price (RMB)
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20μL
598
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50μL
998
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100μL
1798
- 货期:现货
For research use only. Not intended for diagnostic.