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Pyruvate Dehydrogenase E1-alpha subunit Rabbit pAb
db2984
Datasheet
- Background The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]
- Immunogen A synthetic peptide of human Pyruvate Dehydrogenase E1-alpha subunit
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Gene ID
5160
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Swiss Prot
P08559
- Synonyms PDHA; PDHAD; PHE1A; PDHCE1A
- Reactivity Human, Mouse, Rat
- Application WB, IHC, ICC/IF, FC, IP
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Recommended dilution
WB: 1:1000-1:2000
IHC: 1:20-1:100
ICC/IF: 1:20-1:100
FC: 1:20
IP: 1:20-1:50 - Calculated MW 43 kDa
- Observed MW 43 kDa
- Host species Rabbit
- Clonality Polyclonal
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
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订购信息
- Package Price (RMB)
- 20μL 598
- 50μL 998
- 100μL 1798
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
