Phospho-IGF1 Receptor (Tyr1166) Rabbit pAb
Product Name :
Phospho-IGF1 Receptor (Tyr1166) Rabbit pAb
Cat.No.:
db2987
Synonyms :
IGFR; CD221; IGFIR; JTK13
Reactivity :
Human, Mouse, Rat
Host species :
Rabbit
Conjugation/Formulation:Un-conjugated
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Background
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
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Immunogen
A synthetic phosphopeptide corresponding to residues surrounding
Tyr1166 of human INSR/IGF-1R
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Gene ID
3480
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Swiss Prot
P08069
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Synonyms
IGFR; CD221; IGFIR; JTK13
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Reactivity
Human, Mouse, Rat
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Application
WB, IP
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Recommended dilution
WB: 1:1000
IP: 1:20
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Calculated MW
155 kDa
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Observed MW
95 kDa
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Host species
Rabbit
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Clonality
Polyclonal
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Isotype
IgG
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Purity
Affinity Purification
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Conjugation
Un-conjugated
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Storage/Stability
Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
订购信息
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Package
Price (RMB)
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20μL
698
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50μL
1398
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100μL
2398
- 货期:现货
For research use only. Not intended for diagnostic.