MHC Class II Rabbit pAb - diagbio | 戴格生物

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MHC Class II Rabbit pAb

db2990

年底大促

Datasheet

Product Name : MHC Class II Rabbit pAb

Cat.No.: db2990

Synonyms : DPB1; HLA-DP; HLA-DPB; HLA-DP1B

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated

Background HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide of human MHC Class II
Gene ID 3115
Swiss Prot P04440
Synonyms DPB1; HLA-DP; HLA-DPB; HLA-DP1B
Reactivity Human
Application WB, IHC, ICC/IF, IP
Recommended dilution WB: 1:2000-1:10000
IHC: 1:200
ICC/IF: 1:20-1:50
IP: 1:20-1:50
Calculated MW 29 kDa
Observed MW 29 kDa
Host species Rabbit
Clonality Polyclonal
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Storage/Stability Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

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