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TFE3 (BP6180) Rabbit mAb (PBS Only)
db30153-PBS
Datasheet
Product Name : TFE3 (BP6180) Rabbit mAb (PBS Only)
Cat.No.: db30153-PBS
Synonyms : TFEA; RCCP2; RCCX1; bHLHe33
Application：
Reactivity : Human
Host species : Rabbit
Conjugation/Formulation：PBS Only
- Background Transcription factor that acts as a master regulator of lysosomal biogenesis and immune response. Specifically recognizes and binds E-box sequences; efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. Involved in the cellular response to amino acid availability by acting downstream of MTOR: in the presence of nutrients, TFE3 phosphorylation by MTOR promotes its cytosolic retention and subsequent inactivation. Upon starvation or lysosomal stress, inhibition of MTOR induces TFE3 dephosphorylation, resulting in nuclear localization and transcription factor activity .
- Immunogen Synthetic peptide was used as an immunogen
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Swiss Prot
P19532
- Synonyms TFEA; RCCP2; RCCX1; bHLHe33
- Reactivity Human
- Application IHC
- Calculated MW 62 kDa
- Host species Rabbit
- Clonality Monoclonal
- Clonality No. BP6180
- Isotype IgG
- Purity Affinity Purification
- Conjugation Un-conjugated
- Concentration 1 mg/mL
- Formulation PBS Only
- Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.
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Immunohistochemistry of paraffin-embedded human alveolar soft part sarcoma using TFE3 antibody at dilution of 1:200 (200x lens).
订购信息
- Package Price (RMB)
- 可询价
- 货期：现货
相关产品
For research use only. Not intended for diagnostic.
