CDK4 (BP6230) Rabbit mAb (PBS Only) - diagbio | 戴格生物

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Recombinant

CDK4 (BP6230) Rabbit mAb (PBS Only)

db30188-PBS

Datasheet

Product Name : CDK4 (BP6230) Rabbit mAb (PBS Only)

Cat.No.: db30188-PBS

Synonyms : CMM3; PSK-J3

Application：

Reactivity : Human

Host species : Rabbit

Un-conjugated PBS Only

Background Cyclin-dependent kinase-4 (CDK4) is a protein-serine kinase involved in the cell cycle. It is essential for the G1- to S-phase transition during the cell cycle and its expression is primarily controlled at the transcriptional level (PMID:17253961). CCND1- CDK4 axis is not only critical in glial tumor cells but also in stromal-derived cells in the surrounding tumor microenvironment that are vital to sustain tumor outgrowth (PMID:21844184).
Immunogen Cyclin-dependent kinase-4 (CDK4) is a protein-serine kinase involved in the cell cycle. It is essential for the G1- to S-phase transition during the cell cycle and its expression is primarily controlled at the transcriptional level (PMID:17253961). CCND1- CDK4 axis is not only critical in glial tumor cells but also in stromal-derived cells in the surrounding tumor microenvironment that are vital to sustain tumor outgrowth (PMID:21844184)
Swiss Prot P11802
Synonyms CMM3; PSK-J3
Reactivity Human
Application IHC, WB, FC
Calculated MW 34 kDa
Host species Rabbit
Clonality Monoclonal
Clonality No. BP6230
Isotype IgG
Purity Affinity Purification
Conjugation Un-conjugated
Concentration 1 mg/mL
Formulation PBS Only
Storage/Stability Store at -20°C. Recommended to aliquot into single-use vials. Supplied in 1X PBS (pH 7.4). BSA and Azide Free. Stable for 12 months from date of receipt.

Immunohistochemistry of paraffin-embedded human dedifferentiated liposarcoma using CDK4 antibody at dilution of 1:200 (200x lens).

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